SCHEMBL4381958

SCHEMBL4381958

Nc1nc2c(ncn2[C@]2(S)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.53
TGM2 P21980 1/20 0.53
PNP P00491 1/20 0.51
KRAS P01116 2/20 0.50
POLB P06746 3/20 0.49
FUT5 Q11128 1/20 0.49
P2RY6 Q15077 2/20 0.49
P2RY2 P41231 1/20 0.49
P2RY4 P51582 1/20 0.49
NT5E P21589 1/20 0.48
POLA1 P09884 1/20 0.46
P2RX3 P56373 3/20 0.45
DCPS Q96C86 1/20 0.45
P2RX1 P51575 2/20 0.43
P2RX2 Q9UBL9 1/20 0.43
ENPP1 P22413 1/20 0.43
P2RY1 P47900 1/20 0.43
P2RY11 Q96G91 1/20 0.43
P2RX4 Q99571 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301189 0.99 TGM2 (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL4410921 0.89 TGM2 (0.55) POLGTGM2PNPKRASPOLB
SCHEMBL4076696 0.88 POLG (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL401417 0.87 TGM2 (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL309062 0.87 TGM2 (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL8435629 0.87 POLG (0.51) POLGTGM2PNPKRASPOLB
SCHEMBL30697339 0.87 TGM2 (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL8438356 0.86 POLG (0.53) POLGTGM2PNPKRASPOLB
SCHEMBL17359519 0.86 POLG (0.51) POLGTGM2PNPKRASPOLB
SCHEMBL30603197 0.86 TGM2 (0.54) POLGTGM2PNPKRASPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113624862-A Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2021-11-09 CN claimed
CN-116773710-A Kit for covering metabolome and metabolic flow of multiple metabolites and use method 清华大学 2023-09-19 CN disclosed
CN-113624862-B Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2023-04-07 CN disclosed
CN-113624862-A Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2021-11-09 CN disclosed
US-9115380-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-08-25 US disclosed
US-20150191760-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT LLC (US) 2015-07-09 US disclosed
US-9005930-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-04-14 US disclosed
US-20140363876-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES 2014-12-11 US disclosed
US-8846348-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2014-09-30 US disclosed
US-20140221248-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT, LLC (US) 2014-08-07 US disclosed
EP-2010659-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA Epicentre Technologies (US) 2009-01-07 EP disclosed
US-20070281336-A1 Kits and methods for generating 5' capped RNA EPICENTRE TECHNOLOGIES (US) 2007-12-06 US disclosed
WO-2007120863-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES (US) 2007-10-25 WO disclosed