SCHEMBL30698159

SCHEMBL30698159

COC(=O)c1ccco1.COC(=O)c1ccco1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.69
CES2 O00748 1/20 0.64
CES1 P23141 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.60
NPC1 O15118 1/20 0.60
TP53 P04637 1/20 0.60
RAB9A P51151 1/20 0.60
MAPK1 P28482 2/20 0.58
PSMD14 O00487 1/20 0.57
CACNA1B Q00975 1/20 0.57
APBA1 Q02410 1/20 0.57
HTT P42858 2/20 0.55
MAOB P27338 1/20 0.55
TSHR P16473 3/20 0.54
MAPT P10636 2/20 0.54
KDM4E B2RXH2 4/20 0.54
HSD17B10 Q99714 3/20 0.54
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363937 1.00
Hydrochloric Acid SCHEMBL11748963 0.98 KMT2A (0.67) KMT2ACES2CES1SMN1; SMN2NPC1
SCHEMBL22462700 0.92 KMT2A (0.61) KMT2ACES2CES1SMN1; SMN2NPC1
Biphenyl SCHEMBL27624338 0.91 KMT2A (0.59) KMT2ACES2CES1SMN1; SMN2NPC1
Furfural SCHEMBL27165471 0.86 ALDH1A1 (0.58) KMT2ACES2CES1SMN1; SMN2NPC1
SCHEMBL27523198 0.86 KMT2A (0.55) KMT2ACES2CES1SMN1; SMN2NPC1
P-Cresol SCHEMBL27605284 0.86 RAB9A (0.56) KMT2ACES2CES1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL27319234 0.85 KMT2A (0.54) KMT2ACES2CES1SMN1; SMN2NPC1
SCHEMBL28817919 0.83 KMT2A (0.52) KMT2ACES2CES1SMN1; SMN2NPC1
Ethoxycarbonyl Group SCHEMBL28817944 0.83 KMT2A (0.52) KMT2ACES2CES1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524787-B Catalytic oxidative coupling method for methyl furoate 中国科学院大连化学物理研究所 2023-10-13 CN disclosed