Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 6/20 | 0.37 |
| ▸ | FYN | P06241 | 7/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542580 | 0.84 | FYN (0.35) | RIPK2FYNDYRK1ADYRK2CCNA2 | |
| SCHEMBL30698345 | 0.84 | FYN (0.40) | RIPK2FYNDYRK1ADYRK2DYRK1B | |
| SCHEMBL31000256 | 0.83 | FYN (0.34) | RIPK2FYNCDK2 | |
| SCHEMBL31639298 | 0.82 | GABRA1 (0.35) | RIPK2FYNGABRA1GABRG2GABRB3 | |
| SCHEMBL24542576 | 0.82 | FYN (0.33) | RIPK2FYNDYRK1ADYRK2DYRK1B | |
| SCHEMBL27327090 | 0.78 | FLT3 (0.35) | FYN | |
| SCHEMBL27329649 | 0.78 | FLT3 (0.35) | FYN | |
| SCHEMBL31000288 | 0.77 | DYRK1A (0.43) | RIPK2FYNDYRK1ADYRK2DYRK1B | |
| SCHEMBL31739935 | 0.76 | FLT3 (0.40) | FYN | |
| SCHEMBL27330460 | 0.76 | NRAS (0.48) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540248-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023245123-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-21 | — | — | WO | disclosed |