Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698330 | 0.84 | RIPK2 (0.37) | FYNRIPK2DYRK3CCNT1CDK9 | |
| SCHEMBL31000288 | 0.83 | DYRK1A (0.43) | FYNRIPK2DYRK3CCNT1CDK9 | |
| SCHEMBL24542626 | 0.78 | DYRK1A (0.38) | FYNRIPK2DYRK3CCNT1CDK9 | |
| SCHEMBL29682996 | 0.78 | DYRK1A (0.38) | FYNRIPK2DYRK3CCNT1CDK9 | |
| SCHEMBL24542580 | 0.77 | FYN (0.35) | FYNRIPK2DYRK3CCNT1CDK9 | |
| SCHEMBL31639298 | 0.77 | GABRA1 (0.35) | FYNRIPK2 | |
| SCHEMBL31739827 | 0.77 | FLT3 (0.35) | FYNTNF | |
| SCHEMBL27329570 | 0.77 | FLT3 (0.35) | FYNTNF | |
| SCHEMBL27327086 | 0.77 | FLT3 (0.35) | FYNTNF | |
| SCHEMBL27330371 | 0.75 | NRAS (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540248-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023245123-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-21 | — | — | WO | disclosed |