Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27038718 | 1.00 | MAPT (0.43) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7849700 | 0.85 | LMNA (0.51) | MAPTLMNAKDM4EHPGDPKM | |
| SCHEMBL7853834 | 0.85 | MAPT (0.51) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18952659 | 0.81 | MAPT (0.41) | MAPTLMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL31489368 | 0.80 | MAPT (0.44) | MAPTLMNACYP1A2CYP2C9KDM4E | |
| SCHEMBL23030187 | 0.80 | MAPT (0.49) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18952507 | 0.79 | MAPT (0.43) | MAPTLMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL31489608 | 0.78 | MAPT (0.49) | MAPTCYP1A2KDM4EHPGDMEN1 | |
| SCHEMBL7849145 | 0.77 | TSHR (0.49) | MAPTLMNAKDM4EHPGDKMT2A | |
| SCHEMBL16983077 | 0.76 | MAPT (0.50) | MAPTLMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539840-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Neuron23, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244788-A9 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2023244788-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2023-12-21 | — | — | WO | disclosed |