Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31308011 | 1.00 | PDE4B (0.34) | PDE4B | |
| SCHEMBL31308079 | 0.75 | HSD11B1 (0.43) | PDE4B | |
| SCHEMBL31308066 | 0.75 | HRH3 (0.47) | — | |
| SCHEMBL15431905 | 0.71 | DRD4 (0.43) | — | |
| SCHEMBL16828882 | 0.71 | — | — | |
| SCHEMBL31308054 | 0.70 | PDE4B (0.33) | PDE4B | |
| SCHEMBL31308077 | 0.69 | PDE4B (0.34) | PDE4B | |
| SCHEMBL16828890 | 0.68 | — | — | |
| SCHEMBL19308651 | 0.68 | — | — | |
| SCHEMBL7829206 | 0.66 | RAB9A (0.49) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |