Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 5/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700519 | 1.00 | MGLL (0.35) | MGLLHTR2AHTR2CEPHX1EPHX2 | |
| SCHEMBL30700283 | 0.88 | MGLL (0.37) | MGLLHTR2AHTR2CGPR6CCR3 | |
| SCHEMBL30699859 | 0.85 | HTR2A (0.37) | MGLLHTR2AHTR2CGPR6CCR3 | |
| SCHEMBL30700903 | 0.78 | MGLL (0.40) | MGLL | |
| SCHEMBL30700677 | 0.78 | MGLL (0.40) | MGLLEPHX2 | |
| SCHEMBL30700096 | 0.77 | MGLL (0.39) | MGLLHTR2AHTR2CCCR4 | |
| SCHEMBL30700361 | 0.77 | MGLL (0.38) | MGLLHTR2AHTR2CCCR4 | |
| SCHEMBL30700887 | 0.75 | MGLL (0.40) | MGLLHTR2AHTR2CCCR4 | |
| SCHEMBL27139040 | 0.74 | MGLL (0.36) | MGLLHTR2AHTR2CGPR6 | |
| SCHEMBL27154914 | 0.73 | MGLL (0.64) | MGLLHTR2AHTR2CGPR6CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |