Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.40 |
| ▸ | GPR183 | P32249 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.33 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700283 | 0.90 | MGLL (0.37) | MGLL | |
| SCHEMBL30700903 | 0.87 | MGLL (0.40) | MGLL | |
| SCHEMBL30700308 | 0.80 | EPHX2 (0.42) | EPHX2RBP4 | |
| SCHEMBL30700189 | 0.80 | EPHX2 (0.42) | EPHX2RBP4 | |
| SCHEMBL30700328 | 0.80 | MGLL (0.36) | MGLL | |
| SCHEMBL30700235 | 0.80 | MGLL (0.36) | MGLL | |
| SCHEMBL30699870 | 0.79 | MGLL (0.43) | MGLLEPHX2 | |
| SCHEMBL30700071 | 0.79 | MGLL (0.37) | MGLL | |
| SCHEMBL30700049 | 0.79 | MGLL (0.37) | MGLL | |
| SCHEMBL30700566 | 0.78 | RORC (0.36) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |