Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700147 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL27289695 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL27289691 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL30700764 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2ABTK | |
| SCHEMBL30700176 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL30700009 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL30700174 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2A | |
| SCHEMBL30700278 | 0.85 | MGLL (0.46) | MGLLPIM1PDE2ABTK | |
| SCHEMBL27292611 | 0.85 | MGLL (0.63) | MGLLHTR2AHTR2CHCRTR1HCRTR2 | |
| SCHEMBL30700335 | 0.84 | MGLL (0.44) | MGLLPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |