Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | LIPE | Q05469 | 8/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291672 | 0.88 | SCN9A (0.40) | SCN9ASCN10ALIPEF2RCNR1 | |
| SCHEMBL30699964 | 0.88 | SCN9A (0.40) | SCN9ASCN10ALIPEF2RCNR1 | |
| SCHEMBL30699936 | 0.82 | SCN9A (0.41) | SCN9ASCN10ALIPEF2RCNR1 | |
| SCHEMBL27291566 | 0.82 | SCN9A (0.41) | SCN9ASCN10ALIPEF2RCNR1 | |
| SCHEMBL30699973 | 0.82 | SCN9A (0.41) | SCN9ASCN10ALIPEF2RCNR1 | |
| SCHEMBL23091977 | 0.80 | LIPE (0.45) | SCN9ASCN10ALIPEF2RCYP2C9 | |
| SCHEMBL29780686 | 0.78 | MGLL (0.62) | — | |
| SCHEMBL23091908 | 0.78 | MGLL (0.62) | — | |
| SCHEMBL30700397 | 0.76 | BTK (0.42) | SCN9AF2RCNR1TMEM97 | |
| SCHEMBL23091863 | 0.75 | LIPE (0.47) | SCN9ASCN10ALIPEBCHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |