Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.60 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vamicamide SCHEMBL9393264 | 1.00 | KCNH2 (0.65) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Vamicamide SCHEMBL331820 | 1.00 | KCNH2 (0.65) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Vamicamide SCHEMBL9393357 | 0.99 | KCNH2 (0.64) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Vamicamide SCHEMBL4603765 | 0.99 | KCNH2 (0.64) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Aminopentamide Sulfate SCHEMBL251458 | 0.85 | GRIN1 (0.75) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Aminopentamide Sulfate SCHEMBL203612 | 0.80 | GRIN1 (0.68) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Disopyramide SCHEMBL23931452 | 0.79 | KCNH2 (1.00) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| (S)-Disopyramide SCHEMBL41811 | 0.79 | KCNH2 (1.00) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Disopyramide SCHEMBL16153 | 0.79 | KCNH2 (1.00) | KCNH2OPRK1BLMSLC22A2SLC22A1 | |
| Disopyramide SCHEMBL546251 | 0.78 | KCNH2 (0.98) | KCNH2OPRK1BLMSLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720903-B1 | THERMALLY TREATED POLYAMIC AMIDE AEROGEL | BLUESHIFT MAT INC (US) | 2024-02-07 | — | — | EP | disclosed |