Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.34 |
| ▸ | USP2 | O75604 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700811 | 0.82 | KCNH2 (0.33) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL30699870 | 0.76 | MGLL (0.43) | MGLLKCNH2GPR119 | |
| SCHEMBL30700087 | 0.76 | MGLL (0.43) | MGLLKCNH2GPR119 | |
| SCHEMBL30700279 | 0.75 | ERAP1 (0.36) | SMN1; SMN2 | |
| SCHEMBL27246314 | 0.75 | MGLL (0.64) | TEAD1MGLLUSP2CYP3A4CYP1A2 | |
| SCHEMBL27246331 | 0.74 | MGLL (0.49) | TEAD1MGLLUSP2CYP3A4CYP1A2 | |
| SCHEMBL25301235 | 0.73 | USP2 (0.43) | TEAD1MGLLUSP2CYP3A4CYP1A2 | |
| SCHEMBL25326080 | 0.73 | MGLL (0.40) | TEAD1MGLLKCNH2GPR119USP2 | |
| SCHEMBL30945251 | 0.72 | MGLL (0.48) | TEAD1MGLLUSP2CYP3A4CYP1A2 | |
| SCHEMBL30700189 | 0.72 | EPHX2 (0.42) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |