SCHEMBL17050816

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30454767	0.86	ACHE (0.50)	L3MBTL1MAPTRAB9AHPGDKMT2A
	SCHEMBL25355273	0.86	ACHE (0.50)	L3MBTL1MAPTRAB9AHPGDKMT2A
	SCHEMBL25353410	0.84	TRPA1 (0.37)	L3MBTL1MAPTRAB9AKMT2APOLB
	SCHEMBL17050452	0.84	MAPK8 (0.43)	L3MBTL1RAB9AHPGDKMT2APOLB
	SCHEMBL17050467	0.83	KDM4E (0.43)	L3MBTL1MAPTRAB9AKMT2APOLB
	SCHEMBL17050451	0.83	L3MBTL1 (0.41)	L3MBTL1MAPTHPGDKMT2APOLB
	SCHEMBL25355051	0.83	ALOX15 (0.39)	MAPTRAB9AHPGDKMT2APOLB
	SCHEMBL17050453	0.81	ACACB (0.53)	L3MBTL1MAPTRAB9AATMHPGD
	SCHEMBL25355182	0.81	PDE4A (0.39)	L3MBTL1MAPTRAB9AHPGDKMT2A
	SCHEMBL30454375	0.81	GAA (0.38)	L3MBTL1MAPTRAB9AHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.