Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511836 | 0.86 | SLC6A4 (0.50) | SLC6A4MGLLHTR2CHTR2BDAO | |
| SCHEMBL3128370 | 0.85 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B | |
| SCHEMBL3124123 | 0.82 | IDO1 (0.52) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B | |
| SCHEMBL16771120 | 0.82 | SLC6A4 (0.49) | SLC6A4SLC6A2MGLLSLC6A3HTR2C | |
| SCHEMBL31071558 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR2CDAO | |
| Trifluoroacetic Acid SCHEMBL23150549 | 0.79 | MGLL (0.49) | SLC6A4SLC6A2MGLLSLC6A3HTR2C | |
| SCHEMBL2299635 | 0.77 | CARM1 (0.54) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B | |
| SCHEMBL6104835 | 0.76 | SLC6A4 (0.54) | SLC6A4SLC6A2HTR2CHTR2BHTR6 | |
| Hydrochloric Acid SCHEMBL381868 | 0.76 | CARM1 (0.53) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B | |
| SCHEMBL23148926 | 0.75 | MGLL (0.51) | MGLLMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |