Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511836 | 0.91 | SLC6A4 (0.50) | MGLLSLC6A4HTR2CHTR2BDAO | |
| Trifluoroacetic Acid SCHEMBL23152297 | 0.87 | IDO1 (0.47) | MGLLSLC6A4HTR2CHTR2BSLC6A2 | |
| Trifluoroacetic Acid SCHEMBL30945211 | 0.84 | IDO1 (0.47) | SLC6A4HTR2CHTR2BMRGPRX4FFAR4 | |
| Trifluoroacetic Acid SCHEMBL25325427 | 0.84 | SLC6A4 (0.45) | SLC6A4HTR2CHTR2BFFAR1FFAR4 | |
| SCHEMBL23148926 | 0.81 | MGLL (0.51) | MGLLMRGPRX4PIM1PDGFRAS1PR1 | |
| Trifluoroacetic Acid SCHEMBL30945234 | 0.80 | SLC6A4 (0.42) | MGLLSLC6A4P2RX7CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL21722954 | 0.79 | SLC6A4 (0.52) | SLC6A4HTR2CHTR2BFFAR1 | |
| SCHEMBL30700754 | 0.79 | SLC6A4 (0.46) | MGLLSLC6A4HTR2CHTR2BMRGPRX4 | |
| Trifluoroacetic Acid SCHEMBL23091759 | 0.78 | MGLL (0.43) | MGLLSLC6A4P2RX7CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL23091803 | 0.78 | NAAA (0.43) | MGLLSLC6A4HTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094972-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094972-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP4B1, CYP1A1 | MGLL 2162/4885SLC6A4 4083/4885HTR2C 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.