Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | F2R | P25116 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700543 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL30700343 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL27292383 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL27290138 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL30700001 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL27290140 | 0.85 | MGLL (0.44) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL30700403 | 0.84 | MGLL (0.43) | MGLLPIK3CAPRKAA2 | |
| SCHEMBL30700764 | 0.83 | MGLL (0.46) | MGLLTEAD1MCHR1F2RJAK2 | |
| SCHEMBL30700322 | 0.83 | MGLL (0.44) | MGLLTEAD1MCHR1F2RJAK2 | |
| SCHEMBL30700278 | 0.83 | MGLL (0.46) | MGLLTEAD1MCHR1F2RJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |