Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21981712 | 1.00 | MCHR1 (0.53) | MCHR1KCNH2HRH3CYP3A4 | |
| SCHEMBL18154552 | 0.89 | MCHR1 (0.54) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154520 | 0.88 | MCHR1 (0.67) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL21981718 | 0.86 | MCHR1 (0.56) | MCHR1KCNH2HRH3 | |
| SCHEMBL31573838 | 0.86 | MCHR1 (0.56) | MCHR1KCNH2HRH3 | |
| SCHEMBL18154575 | 0.84 | MCHR1 (0.52) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154568 | 0.84 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL21981715 | 0.83 | MCHR1 (0.56) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL18154555 | 0.83 | MCHR1 (0.51) | MCHR1KCNH2CYP3A4 | |
| Fumaric Acid SCHEMBL18154588 | 0.83 | MCHR1 (0.61) | MCHR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242810-A1 | MCHR1 ANTAGONISTS FOR THE TREATMENT OF PRADER-WILLI SYNDROME | RICHTER GEDEON NYRT. (HU) | 2023-12-21 | — | — | WO | claimed |
| WO-2023242810-A1 | MCHR1 ANTAGONISTS FOR THE TREATMENT OF PRADER-WILLI SYNDROME | RICHTER GEDEON NYRT. (HU) | 2023-12-21 | — | — | WO | disclosed |