Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18154555 | 0.99 | MCHR1 (0.51) | MCHR1KCNH2HTR2AHTR2CCYP3A4 | |
| SCHEMBL18154559 | 0.87 | MCHR1 (0.66) | MCHR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL18154562 | 0.86 | MCHR1 (0.65) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154552 | 0.86 | MCHR1 (0.54) | MCHR1KCNH2HTR2AHTR2CCYP3A4 | |
| SCHEMBL18154553 | 0.86 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL30700892 | 0.84 | MCHR1 (0.53) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL21981712 | 0.84 | MCHR1 (0.53) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL18154564 | 0.83 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL18154557 | 0.82 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL18154531 | 0.82 | MCHR1 (0.58) | MCHR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |