Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463642 | 1.00 | MIF (0.49) | MIFSMN1; SMN2NAAAALDH1A1PRKCA | |
| SCHEMBL3069917 | 0.93 | NAAA (0.56) | MIFNAAAALDH1A1PRKCATDP1 | |
| SCHEMBL9764170 | 0.89 | MIF (0.47) | MIFSMN1; SMN2ALDH1A1PRKCATDP1 | |
| SCHEMBL9405650 | 0.87 | SMN1; SMN2 (0.48) | MIFSMN1; SMN2NAAAALDH1A1PRKCA | |
| SCHEMBL7803427 | 0.80 | — | — | |
| SCHEMBL7804568 | 0.80 | — | — | |
| SCHEMBL3062283 | 0.80 | — | — | |
| SCHEMBL10309225 | 0.80 | DGKA (0.53) | SMN1; SMN2ALDH1A1PRKCADGKA | |
| SCHEMBL1685769 | 0.80 | TSHR (0.45) | MIFSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL28263792 | 0.79 | MGAM (0.44) | MIFALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261251-A1 | MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-10-14 | — | — | US | disclosed |
| EP-2179050-A1 | MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE | Agency for Science, Technology And Research (SG) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009008834-A1 | MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-01-15 | — | — | WO | disclosed |
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0237080-A2 | Process for the preparation of L(-)-carnitine chloride starting from 3,4-epoxybutyric esters | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-09-16 | — | — | EP | disclosed |