SCHEMBL30701075

SCHEMBL30701075

COc1cc(C(=O)CCN(C)C)c(OC)c(OC)n1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
STAT6 P42226 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAOB P27338 2/20 0.42
MAOA P21397 1/20 0.42
THRB P10828 9/20 0.39
THRA P10827 8/20 0.39
POLB P06746 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL4 Q8NA19 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
TERT O14746 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19330612 1.00 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP3A4CYP2C9STAT6
SCHEMBL19330426 0.77 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP3A4CYP2C9STAT6
SCHEMBL19330148 0.77 TDP1 (0.61) ALDH1A1CYP1A2HSD17B10POLBTDP1
SCHEMBL19330152 0.76 ALDH1A1 (0.55) ALDH1A1CYP1A2HSD17B10POLBTDP1
SCHEMBL19330334 0.75 POLB (0.41) ALDH1A1CYP1A2HSD17B10POLBTDP1
SCHEMBL30701127 0.75 POLB (0.41) ALDH1A1CYP1A2HSD17B10POLBTDP1
SCHEMBL26731664 0.72 THRA (0.44) ALDH1A1CYP1A2CYP3A4CYP2C9STAT6
SCHEMBL19330767 0.71 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP3A4CYP2C9STAT6
SCHEMBL30701055 0.71 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP3A4CYP2C9STAT6
SCHEMBL19330798 0.70 THRA (0.46) ALDH1A1THRBTHRAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069514-B Antibacterial compound and application thereof 结核病药物开发全球联盟公司 2023-12-29 CN disclosed