Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806654 | 1.00 | MAP2K1 (0.48) | MAP2K1FFAR1FFAR4PTGDR2CXCR1 | |
| SCHEMBL2773527 | 0.92 | MAP2K1 (0.43) | MAP2K1FFAR1FFAR4PTGDR2CXCR1 | |
| SCHEMBL8118450 | 0.88 | MAP2K1 (0.45) | MAP2K1FFAR1FFAR4PTGDR2EGLN1 | |
| SCHEMBL13542003 | 0.81 | KDM4E (0.53) | MAP2K1FFAR1PTGDR2CXCR1CXCR2 | |
| SCHEMBL18112296 | 0.79 | MAP2K1 (0.51) | MAP2K1FFAR1FFAR4CXCR1CXCR2 | |
| SCHEMBL19133477 | 0.79 | KAT2B (0.44) | MAP2K1FFAR1FFAR4CXCR1CXCR2 | |
| SCHEMBL30882179 | 0.78 | ALDH1A1 (0.50) | PKMALDH1A1MAPT | |
| SCHEMBL188080 | 0.78 | ALDH1A1 (0.50) | PKMALDH1A1MAPT | |
| SCHEMBL8113563 | 0.78 | PTGDR2 (0.43) | PTGDR2EGLN1MEN1KMT2AFLT1 | |
| SCHEMBL8114370 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4PTGDR2EGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117224537-A | Application of 2-fludarifenacin chlorine-containing derivative in preparation of medicines for inhibiting and treating colon cancer | 浙江广厦建设职业技术大学 | 2023-12-15 | — | — | CN | disclosed |