Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993926 | 0.88 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAHTTMAPT | |
| SCHEMBL16155889 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1GAAHTTMAPT | |
| SCHEMBL2773527 | 0.83 | MAP2K1 (0.43) | KDM4EALDH1A1GAACXCR2CXCR1 | |
| SCHEMBL30701079 | 0.81 | MAP2K1 (0.48) | ALDH1A1MAPTCXCR2CXCR1KAT2B | |
| SCHEMBL2806654 | 0.81 | MAP2K1 (0.48) | ALDH1A1MAPTCXCR2CXCR1KAT2B | |
| SCHEMBL15595142 | 0.80 | LMNA (0.44) | KDM4EALDH1A1GAAHTTMAPT | |
| SCHEMBL1649137 | 0.79 | ABCB1 (0.47) | KDM4EALDH1A1GAAHTTMAPT | |
| SCHEMBL8113563 | 0.78 | PTGDR2 (0.43) | ALDH1A1GAAMAPTPTGDR2EGLN1 | |
| SCHEMBL8114370 | 0.78 | FFAR1 (0.46) | KDM4EALDH1A1GAAMAPTPTGDR2 | |
| SCHEMBL8118450 | 0.78 | MAP2K1 (0.45) | PTGDR2EGLN1FLT1EGLN3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005087-A1 | AMIDINE DERIVATIVE | 味の素株式会社 (JP) | 2010-01-14 | — | — | WO | disclosed |