Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINH1 | P50454 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29116805 | 1.00 | SERPINH1 (0.43) | SERPINH1ALPLMEN1KMT2AMAPT | |
| SCHEMBL31056113 | 0.82 | L3MBTL1 (0.39) | MAPTNR4A2KDM4EMAPK1SLC6A3 | |
| SCHEMBL29267953 | 0.82 | L3MBTL1 (0.39) | MAPTNR4A2KDM4EMAPK1SLC6A3 | |
| SCHEMBL19612178 | 0.81 | AKR1C4 (0.42) | ALPLMEN1KMT2AKDM4ETSHR | |
| SCHEMBL2011769 | 0.75 | KDM4E (0.43) | MEN1KMT2AMAPTNR4A2KDM4E | |
| SCHEMBL16197979 | 0.74 | MEN1 (0.42) | SERPINH1MEN1KMT2AMAPTABL1 | |
| SCHEMBL31464259 | 0.73 | RHEB (0.39) | ALPLMEN1KMT2AMAPTABL1 | |
| SCHEMBL1080968 | 0.73 | TSHR (0.47) | SERPINH1ALPLMEN1KMT2AMAPT | |
| SCHEMBL20541577 | 0.71 | CHEK1 (0.50) | SERPINH1MEN1KMT2AABL1NR4A2 | |
| SCHEMBL2427967 | 0.71 | GAA (0.41) | ALPLMAPTABL1NR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164529-A | EP2 and EP4 antagonists | 武汉人福创新药物研发中心有限公司 | 2023-12-05 | — | — | CN | disclosed |