Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267953 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NR4A2MAPK1TSHRHSD17B10 | |
| SCHEMBL30701408 | 0.82 | SERPINH1 (0.43) | L3MBTL1NR4A2MAPK1TSHRALDH1A1 | |
| SCHEMBL29116805 | 0.82 | SERPINH1 (0.43) | L3MBTL1NR4A2MAPK1TSHRALDH1A1 | |
| SCHEMBL24597269 | 0.81 | AKR1C3 (0.42) | HSD17B10KDM4EGLA | |
| SCHEMBL30591117 | 0.76 | NR4A2 (0.41) | L3MBTL1NR4A2TSHRHSD17B10GAA | |
| SCHEMBL15973251 | 0.76 | NR4A2 (0.41) | L3MBTL1NR4A2MAPK1TSHRHSD17B10 | |
| SCHEMBL25395312 | 0.76 | NR4A2 (0.41) | L3MBTL1NR4A2TSHRHSD17B10GAA | |
| SCHEMBL30618047 | 0.76 | NR4A2 (0.41) | L3MBTL1NR4A2MAPK1TSHRHSD17B10 | |
| SCHEMBL2011769 | 0.75 | KDM4E (0.43) | L3MBTL1NR4A2TSHRHSD17B10GAA | |
| SCHEMBL31512853 | 0.74 | NR4A2 (0.39) | L3MBTL1NR4A2MAPK1TSHRXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |