Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17396689 | 1.00 | GRM4 (0.41) | GRM4SMARCA2RECQLLOXLOXL3 | |
| SCHEMBL15357773 | 0.80 | ALDH1A1 (0.39) | SMARCA2RECQLLOXLOXL3LOXL2 | |
| SCHEMBL27958617 | 0.78 | GRM4 (0.39) | GRM4RECQLPDE4DROCK1MAPT | |
| SCHEMBL17842654 | 0.77 | PDE8A (0.44) | SMARCA2RECQLLOXLOXL3LOXL2 | |
| SCHEMBL17923115 | 0.76 | NOS3 (0.57) | GRM4ROCK1KMT2AMEN1KDM4E | |
| SCHEMBL31375526 | 0.76 | GRM4 (0.38) | GRM4RECQLROCK1MAPTRAB9A | |
| SCHEMBL16579461 | 0.76 | UHRF1 (0.45) | GRM4RECQLROCK1MAPTKDM4E | |
| SCHEMBL29598523 | 0.76 | NOS3 (0.57) | GRM4ROCK1KMT2AMEN1KDM4E | |
| SCHEMBL17923112 | 0.76 | GRM4 (0.38) | GRM4RECQLROCK1MAPTRAB9A | |
| SCHEMBL31610834 | 0.76 | UHRF1 (0.45) | GRM4RECQLROCK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547657-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119384415-A | CD73 compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024006929-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |