Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191919 | 1.00 | TRPV4 (0.45) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL21543270 | 0.92 | TRPV4 (0.45) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL28831695 | 0.83 | ALDH1A1 (0.42) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL8462168 | 0.82 | TRPV4 (0.52) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL31504178 | 0.80 | TRPV4 (0.56) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL1880028 | 0.80 | TRPV4 (0.56) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL14720036 | 0.80 | TRPV4 (0.50) | TRPV4KHKCYP11B2CYP11B1EGLN2 | |
| SCHEMBL29559549 | 0.80 | TRPV4 (0.50) | TRPV4KHKCYP11B2CYP11B1EGLN2 | |
| SCHEMBL832660 | 0.79 | TRPV4 (0.45) | TRPV4KHKCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL1630792 | 0.76 | TRPV4 (0.56) | TRPV4KHKCYP11B2CYP11B1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |