Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191977 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL287220 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL2888545 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL23113725 | 0.79 | MEN1 (0.52) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL1607866 | 0.78 | TP53 (0.55) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL940807 | 0.78 | TP53 (0.55) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL29999860 | 0.78 | NPC1 (0.46) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL27089356 | 0.78 | NPC1 (0.46) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL11718597 | 0.77 | GAA (0.48) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL11722198 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |