Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27089356 | 1.00 | NPC1 (0.46) | NPC1MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL29960870 | 0.84 | NPC1 (0.61) | NPC1MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL29083934 | 0.84 | NPC1 (0.61) | NPC1MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL27191977 | 0.78 | ALDH1A1 (0.42) | MAPTPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL30702064 | 0.78 | ALDH1A1 (0.42) | MAPTPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL10754805 | 0.76 | MAPK1 (0.50) | MAPTPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL17516281 | 0.76 | ATM (0.49) | POLBCYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL14534667 | 0.75 | MAPT (0.46) | NPC1MAPTPOLBGLAKMT2A | |
| SCHEMBL31310325 | 0.73 | MAPT (0.45) | NPC1MAPTPOLBGLAKMT2A | |
| SCHEMBL25219283 | 0.73 | HCAR2 (0.46) | MAPTPOLBCYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216762-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2022-10-13 | — | — | WO | disclosed |