Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797501 | 1.00 | P2RX7 (0.45) | P2RX7NOTUMRAB9AKCNMA1OPRM1 | |
| SCHEMBL17295764 | 0.82 | P2RX7 (0.45) | P2RX7NOTUMRAB9AKCNMA1KCNH2 | |
| SCHEMBL15060116 | 0.81 | NOTUM (0.45) | P2RX7NOTUMRAB9AKCNMA1OPRM1 | |
| SCHEMBL30379474 | 0.81 | NOTUM (0.45) | P2RX7NOTUMRAB9AKCNMA1OPRM1 | |
| SCHEMBL25260855 | 0.79 | OPRM1 (0.36) | OPRM1OPRD1OPRK1TSHRHTT | |
| SCHEMBL31234419 | 0.79 | NOTUM (0.41) | P2RX7NOTUMRAB9AKCNMA1OPRM1 | |
| SCHEMBL16753902 | 0.77 | NOTUM (0.52) | NOTUMKCNMA1HDAC8CA1CA2 | |
| SCHEMBL30994998 | 0.77 | NOTUM (0.52) | NOTUMKCNMA1HDAC8CA1CA2 | |
| SCHEMBL29479362 | 0.76 | NOTUM (0.50) | P2RX7NOTUMRAB9AKCNMA1OPRM1 | |
| SCHEMBL20359547 | 0.76 | NOTUM (0.50) | P2RX7NOTUMRAB9AKCNMA1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |