Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702371 | 0.86 | KDR (0.56) | METKDRDDR2AURKALCK | |
| SCHEMBL3899101 | 0.86 | KDR (0.66) | METKDRAURKALCKTEK | |
| SCHEMBL30702343 | 0.83 | SCN8A (0.41) | METKDRAURKALCKTEK | |
| SCHEMBL30051204 | 0.82 | DDR2 (0.56) | METKDRDDR2AURKALCK | |
| SCHEMBL29186585 | 0.82 | DDR2 (0.56) | METKDRDDR2AURKALCK | |
| SCHEMBL18412897 | 0.76 | SLC22A12 (0.50) | LMNAKDM4EMAPTTSHRHTT | |
| SCHEMBL3892890 | 0.75 | KDR (0.67) | METKDRAURKALCKTEK | |
| SCHEMBL3894634 | 0.75 | SRC (0.64) | METKDRLMNASRCTGFBR1 | |
| SCHEMBL30050441 | 0.75 | EGFR (0.58) | KDRDDR2NPC1NCOA1NCOA3 | |
| SCHEMBL27159593 | 0.75 | EGFR (0.58) | KDRDDR2NPC1NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321036-A | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity | 成都安泰康赛生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |