Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | MET | P08581 | 3/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | TEK | Q02763 | 1/20 | 0.56 |
| ▸ | AXL | P30530 | 5/20 | 0.52 |
| ▸ | SRC | P12931 | 5/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | PDXK | O00764 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899101 | 0.91 | KDR (0.66) | KDRMETAURKBAURKALCK | |
| SCHEMBL30702349 | 0.86 | MET (0.50) | KDRMETAURKBAURKALCK | |
| SCHEMBL29186574 | 0.82 | KDR (0.52) | KDRMETAURKBAURKALCK | |
| SCHEMBL3894634 | 0.81 | SRC (0.64) | KDRMETSRCTGFBR1PDGFRA | |
| SCHEMBL3892890 | 0.81 | KDR (0.67) | KDRMETAURKBAURKALCK | |
| SCHEMBL4656863 | 0.80 | KDR (0.68) | KDRMETAURKBAURKALCK | |
| SCHEMBL3896063 | 0.79 | SRC (0.78) | KDRMETAXLSRCTGFBR1 | |
| Hydrochloric Acid SCHEMBL3892765 | 0.78 | SRC (0.77) | KDRMETAXLSRCTGFBR1 | |
| SCHEMBL1890635 | 0.78 | AXL (0.65) | KDRMETAURKBAURKALCK | |
| SCHEMBL22106609 | 0.78 | AXL (0.70) | KDRMETAURKBAURKALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321036-A | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity | 成都安泰康赛生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |