SCHEMBL30705187

SCHEMBL30705187

Cc1ccnc(-c2cccc(O)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.57
HSD17B1 P14061 8/20 0.56
HSD17B2 P37059 8/20 0.56
CCR1 P32246 1/20 0.55
CCR5 P51681 1/20 0.55
CCR8 P51685 1/20 0.55
CNR1 P21554 1/20 0.50
ACHE P22303 1/20 0.50
KDM1A O60341 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
PIK3CA P42336 1/20 0.47
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
FYN P06241 2/20 0.45
KMO O15229 1/20 0.45
CYP19A1 P11511 1/20 0.45
METAP2 P50579 1/20 0.45
MAPKAPK2 P49137 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23525600 1.00 CYP2A6 (0.57) CYP2A6HSD17B1HSD17B2CCR1CCR5
SCHEMBL12408987 0.85 CYP2A6 (0.65) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL2479816 0.80 CYP2A6 (0.59) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL17406767 0.79 CCR1 (0.61) CYP2A6CCR1CCR5CCR8ACHE
SCHEMBL23259447 0.79 CYP2A6 (0.58) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL9014388 0.79 CCR1 (0.74) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL21386946 0.79 CCR1 (0.74) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL29446990 0.79 CYP2A6 (0.67) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL842170 0.79 CYP2A6 (0.67) CYP2A6CCR1CCR5CCR8CNR1
SCHEMBL9014049 0.79 CCR1 (0.74) CYP2A6CCR1CCR5CCR8CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279468-A Phosphorescent excimer with preferred molecular orientation as monochromatic emitter for display and illumination applications 李健 2023-12-22 CN disclosed