SCHEMBL30705196

SCHEMBL30705196

C=CCOc1ccc(S(=O)(=O)c2ccccc2O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
POLB P06746 2/20 0.46
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
KAT6A Q92794 4/20 0.42
SLC5A1 P13866 1/20 0.40
SLC5A2 P31639 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
MMP2 P08253 3/20 0.40
MMP12 P39900 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705198 1.00 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL1794492 0.88 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL1794491 0.88 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL1548953 0.84 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL1794276 0.83 MMP2 (0.50) CA12CA1CA2CA7CA9
SCHEMBL1793545 0.83 ALDH1A1 (0.45) CA12CA1CA2CA7CA9
SCHEMBL1793050 0.82 MMP2 (0.49) CA12CA1CA2CA7CA9
SCHEMBL1791608 0.82 MMP2 (0.49) CA12CA1CA2CA7CA9
SCHEMBL536507 0.81 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL1793533 0.81 CA12 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117098671-A Compositions and methods for sensitizing thermal media 索理思科技开曼公司 2023-11-21 CN claimed