Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.36 |
| ▸ | CDK2 | P24941 | 5/20 | 0.36 |
| ▸ | CDK9 | P50750 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | YES1 | P07947 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | FGR | P09769 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.34 |
| ▸ | ABL2 | P42684 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240392 | 1.00 | CCNT1 (0.36) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24240376 | 0.89 | EGFR (0.38) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24240390 | 0.88 | EGFR (0.44) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24240383 | 0.87 | MKNK1 (0.45) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL30705259 | 0.87 | MKNK1 (0.45) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24496878 | 0.84 | EGFR (0.47) | EGFR | |
| SCHEMBL30705253 | 0.79 | EGFR (0.37) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24240378 | 0.79 | EGFR (0.37) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL24496892 | 0.78 | EGFR (0.39) | CCNT1CCNE1CDK2CDK9EGFR | |
| SCHEMBL29162975 | 0.78 | EGFR (0.38) | CCNT1CCNE1CDK2CDK9EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747950-B | Pyrimidine derivatives for the treatment of cancer | 深圳福沃药业有限公司 | 2024-01-23 | — | — | CN | disclosed |