Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22509195 | 1.00 | GSK3B (0.44) | GSK3BCDK2KMT2APRKCAKDM4E | |
| SCHEMBL24240371 | 0.88 | GSK3B (0.34) | GSK3BCDK2KMT2AKDM4EGSK3A | |
| SCHEMBL22509160 | 0.88 | GSK3B (0.46) | GSK3BCDK2KMT2APRKCAKDM4E | |
| SCHEMBL30705246 | 0.88 | GSK3B (0.46) | GSK3BCDK2KMT2APRKCAKDM4E | |
| SCHEMBL22509188 | 0.84 | GSK3B (0.49) | GSK3BPRKCAKDM4EGSK3ALMNA | |
| SCHEMBL30705252 | 0.84 | GSK3B (0.49) | GSK3BPRKCAKDM4EGSK3ALMNA | |
| SCHEMBL29025136 | 0.83 | KDM4E (0.47) | GSK3BCDK2PRKCAKDM4EPOLB | |
| SCHEMBL28987624 | 0.81 | DYRK1A (0.43) | GSK3BCDK2KMT2APRKCAKDM4E | |
| SCHEMBL30337437 | 0.81 | DYRK1A (0.43) | GSK3BCDK2KMT2APRKCAKDM4E | |
| SCHEMBL22509235 | 0.76 | GSK3B (0.44) | GSK3BCDK2KDM4ECDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747950-B | Pyrimidine derivatives for the treatment of cancer | 深圳福沃药业有限公司 | 2024-01-23 | — | — | CN | disclosed |