Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264707 | 0.83 | CHRNB2 (0.46) | CHRNA7HRH1HTR2ACHRNB2CHRNA4 | |
| SCHEMBL905971 | 0.81 | CFTR (0.46) | KCNH2SLC6A2SLC6A4CFTRSLC6A3 | |
| SCHEMBL906141 | 0.81 | CFTR (0.46) | KCNH2SLC6A2SLC6A4CFTRSLC6A3 | |
| SCHEMBL20319037 | 0.81 | CFTR (0.46) | KCNH2SLC6A2SLC6A4CFTRSLC6A3 | |
| SCHEMBL11298123 | 0.80 | CHRNA7 (0.49) | CHRNA7HRH1HTR2ACHRNB2CHRNA4 | |
| SCHEMBL4506098 | 0.78 | HTR2A (0.67) | HRH1HTR2ACYP2D6CHRM1KCNH2 | |
| SCHEMBL2680525 | 0.78 | HTR2A (0.67) | HRH1HTR2ACYP2D6CHRM1KCNH2 | |
| SCHEMBL8179214 | 0.78 | CFTR (0.43) | KCNH2SLC6A2SLC6A4CFTRSLC6A3 | |
| SCHEMBL14786230 | 0.78 | L3MBTL1 (0.46) | CYP2D6CYP3A4KCNH2SLC6A2SLC6A4 | |
| SCHEMBL17483463 | 0.77 | SMN1; SMN2 (0.47) | KCNH2SLC6A2SLC6A4CFTRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098765-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |