Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706118 | 0.94 | HTR6 (0.46) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL30705958 | 0.94 | HTR6 (0.46) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL30794148 | 0.90 | JAK2 (0.44) | HTR6BCHEIRAK1ACKR3PRMT5 | |
| SCHEMBL30794238 | 0.90 | JAK2 (0.44) | HTR6BCHEIRAK1ACKR3PRMT5 | |
| SCHEMBL30706001 | 0.87 | HTR6 (0.42) | HTR6BCHEIRAK1CYP2C9USP30 | |
| SCHEMBL30705911 | 0.86 | HTR6 (0.46) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL30662968 | 0.85 | PRMT5 (0.43) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL30735134 | 0.85 | PRMT5 (0.43) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL30663067 | 0.85 | PRMT5 (0.43) | HTR6BCHEIRAK1ACKR3USP30 | |
| SCHEMBL26636990 | 0.85 | PRMT5 (0.43) | HTR6BCHEIRAK1ACKR3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536649-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |