Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30794238 | 1.00 | JAK2 (0.44) | JAK2JAK3PTK2PRMT5IDO1 | |
| SCHEMBL30705958 | 0.96 | HTR6 (0.46) | JAK2JAK3PTK2PRMT5IDO1 | |
| SCHEMBL30706118 | 0.96 | HTR6 (0.46) | JAK2JAK3PTK2PRMT5IDO1 | |
| SCHEMBL30705933 | 0.90 | HTR6 (0.44) | PRMT5HTR6BCHEIRAK1MERTK | |
| SCHEMBL30706133 | 0.87 | ACACB (0.42) | PRMT5 | |
| SCHEMBL24754832 | 0.87 | TLR9 (0.40) | PRMT5CCNT1CDK9 | |
| SCHEMBL30029738 | 0.87 | TLR9 (0.40) | PRMT5CCNT1CDK9 | |
| SCHEMBL30794350 | 0.87 | PRMT5 (0.42) | JAK2JAK3PTK2PRMT5IDO1 | |
| SCHEMBL30794025 | 0.87 | PRMT5 (0.42) | JAK2JAK3PTK2PRMT5IDO1 | |
| SCHEMBL30794352 | 0.87 | PRMT5 (0.42) | JAK2JAK3PTK2PRMT5IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536658-A1 | 1,8-NAPHTHYRIDIN-2-ONE HETEROBIFUNCTIONAL BCL6 DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |