Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706131 | 0.93 | PRMT5 (0.56) | PRMT5GPR119YAP1KDM4EPKM | |
| SCHEMBL30705912 | 0.91 | GPR119 (0.48) | PRMT5GPR119YAP1KDM4EPKM | |
| SCHEMBL30768437 | 0.88 | PRMT5 (0.54) | PRMT5GPR119YAP1CCNT1CCNA2 | |
| SCHEMBL31382255 | 0.86 | PRMT5 (0.53) | PRMT5GPR119YAP1 | |
| SCHEMBL30706140 | 0.85 | ACKR3 (0.51) | PRMT5GPR119 | |
| SCHEMBL30706023 | 0.85 | ACKR3 (0.51) | PRMT5GPR119 | |
| SCHEMBL24206930 | 0.85 | PRMT5 (0.52) | PRMT5GPR119YAP1 | |
| SCHEMBL29223506 | 0.83 | PRMT5 (0.53) | PRMT5GPR119YAP1 | |
| SCHEMBL24670554 | 0.83 | GPR119 (0.47) | PRMT5GPR119YAP1KDM4EPKM | |
| SCHEMBL29990523 | 0.83 | GPR119 (0.47) | PRMT5GPR119YAP1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536649-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |