Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707648 | 0.76 | KMT2A (0.57) | KMT2AALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL12488367 | 0.76 | CFTR (0.43) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL1920431 | 0.70 | CFTR (0.46) | KMT2AALDH1A1KDM4EHPGDNR4A2 | |
| SCHEMBL30280800 | 0.70 | CFTR (0.46) | KMT2AALDH1A1KDM4EHPGDNR4A2 | |
| SCHEMBL2452734 | 0.69 | ABL1 (0.61) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL29752578 | 0.69 | ABL1 (0.61) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL26661413 | 0.69 | ABL1 (0.61) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL1016173 | 0.69 | ABL1 (0.66) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL29406512 | 0.69 | ABL1 (0.61) | ABL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL1197244 | 0.68 | ABL1 (0.64) | ABL1KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540238-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | Monte Rosa Therapeutics AG (CH) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244818-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |