Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619892 | 0.80 | KMT2A (0.67) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL3972158 | 0.80 | ALDH1A1 (0.45) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2878827 | 0.80 | KDM4E (0.61) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL417476 | 0.77 | SERPINE1 (0.56) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL30707631 | 0.76 | ABL1 (0.40) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL23603155 | 0.75 | F10 (0.64) | KMT2AKDM4ENPSR1ALDH1A1HPGD | |
| SCHEMBL4158012 | 0.75 | KMT2A (0.52) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL12488367 | 0.75 | CFTR (0.43) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL22075849 | 0.73 | POLB (0.69) | KMT2APOLBKDM4ENPSR1ALDH1A1 | |
| SCHEMBL7572659 | 0.73 | KMT2A (0.69) | KMT2APOLBKDM4ENPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540238-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | Monte Rosa Therapeutics AG (CH) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244818-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |