SCHEMBL30707869

SCHEMBL30707869

Clc1cccc(C#Cc2cccc(Cl)c2)c1

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.67
GRM5 P41594 10/20 0.60
CYP2C9 P11712 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.47
MAOB P27338 1/20 0.46
CYP2D6 P10635 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
APP P05067 1/20 0.43
HAO1 Q9UJM8 1/20 0.42
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4562631 1.00 KCNH2 (0.67) KCNH2GRM5CYP2C9PTGDR2MAOB
Charcoal, Activated SCHEMBL31286308 0.97 KCNH2 (0.64) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL717449 0.93 KCNH2 (0.60) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL30081497 0.91 KCNH2 (0.58) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL28630419 0.91 KCNH2 (0.58) KCNH2GRM5CYP2C9PTGDR2MAOB
Ammonia Solution, Strong SCHEMBL5555414 0.89 KCNH2 (0.56) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL25490062 0.87 KCNH2 (0.55) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL29978649 0.87 KCNH2 (0.55) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL718734 0.87 KCNH2 (0.55) KCNH2GRM5CYP2C9PTGDR2MAOB
SCHEMBL29794004 0.87 KCNH2 (0.59) KCNH2GRM5MAOBCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371309-A Indenoacetates method for synthesizing compound 南通大学 2025-01-28 CN claimed
CN-117285454-A Synthesis method of indole derivative and benzodipyrrole derivative 南京邮电大学 2023-12-26 CN claimed
CN-119371309-A Indenoacetates method for synthesizing compound 南通大学 2025-01-28 CN disclosed
CN-119346167-A Catalytic system and method for synthesizing diaryl acetylene from calcium carbide and iodo aromatic hydrocarbon 石河子大学 2025-01-24 CN disclosed
CN-117285454-A Synthesis method of indole derivative and benzodipyrrole derivative 南京邮电大学 2023-12-26 CN disclosed