Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 10/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707869 | 1.00 | KCNH2 (0.67) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| Charcoal, Activated SCHEMBL31286308 | 0.97 | KCNH2 (0.64) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL717449 | 0.93 | KCNH2 (0.60) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL30081497 | 0.91 | KCNH2 (0.58) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL28630419 | 0.91 | KCNH2 (0.58) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| Ammonia Solution, Strong SCHEMBL5555414 | 0.89 | KCNH2 (0.56) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL25490062 | 0.87 | KCNH2 (0.55) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL29978649 | 0.87 | KCNH2 (0.55) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL718734 | 0.87 | KCNH2 (0.55) | KCNH2GRM5CYP2C9PTGDR2MAOB | |
| SCHEMBL29794004 | 0.87 | KCNH2 (0.59) | KCNH2GRM5MAOBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285454-A | Synthesis method of indole derivative and benzodipyrrole derivative | 南京邮电大学 | 2023-12-26 | — | — | CN | claimed |
| CN-110028394-B | Synthetic method of indanone and derivatives thereof | 南京邮电大学 | 2021-09-17 | — | — | CN | claimed |
| EP-1292604-B1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LTD (GB) | 2009-05-13 | — | — | EP | claimed |
| CN-117285454-A | Synthesis method of indole derivative and benzodipyrrole derivative | 南京邮电大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-110028394-B | Synthetic method of indanone and derivatives thereof | 南京邮电大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-106518634-B | A kind of preparation method of photocatalysis α-dione compounds | 大连理工大学 | 2019-03-05 | — | — | CN | disclosed |
| US-9493494-B2 | Phosphinine oxide derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
| US-5178791-A | Ferroelectricity; electrooptics | DISPLAYTECH, INC. (US) | 1993-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | PHOSPHO1, PPIP5K2, ITPA | KCNH2 2296/4885GRM5 732/4885CYP2C9 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.