Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | XPO1 | O14980 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860490 | 1.00 | PIK3CD (0.42) | PIK3CDXPO1LMNAMAPTALDH1A1 | |
| SCHEMBL29666619 | 0.88 | ALDH1A1 (0.42) | XPO1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL24460923 | 0.88 | ALDH1A1 (0.42) | XPO1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL26694482 | 0.85 | MEN1 (0.42) | PIK3CDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL24649338 | 0.84 | LMNA (0.39) | PIK3CDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2421138 | 0.83 | XPO1 (0.47) | XPO1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL31715974 | 0.82 | XPO1 (0.40) | XPO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2974934 | 0.82 | XPO1 (0.40) | XPO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1862955 | 0.81 | LMNA (0.40) | PIK3CDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL15232439 | 0.81 | PIK3CA (0.44) | PIK3CDLMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547666-A1 | METHODS FOR TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006445-A1 | METHODS FOR TREATMENT OF CANCER | FRONTIER MEDICINES CORPORATION (US) | 2024-01-04 | — | — | WO | disclosed |