Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.58 |
| ▸ | PARG | Q86W56 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26603330 | 1.00 | HIF1A (0.58) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603358 | 0.92 | HIF1A (0.68) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603518 | 0.90 | ALDH1A1 (0.64) | ALDH1A1USP2MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL30709071 | 0.90 | HIF1A (0.58) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603382 | 0.90 | HIF1A (0.58) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603260 | 0.87 | PARG (0.61) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603402 | 0.87 | ALDH1A1 (0.66) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL26603242 | 0.86 | HIF1A (0.67) | HIF1APARGALDH1A1USP2MAPK1 | |
| SCHEMBL30709143 | 0.85 | PARG (0.58) | HIF1APARGUSP2MAPK1LMNA | |
| SCHEMBL26603424 | 0.85 | PARG (0.58) | HIF1APARGUSP2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903563-A | GPCR modulators and uses thereof | 北京昌平实验室 | 2023-10-20 | — | — | CN | disclosed |