SCHEMBL3071001

SCHEMBL3071001

Clc1[c]c2ccccc2c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.40
CYP1A2 P05177 4/20 0.40
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AHR P35869 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CCR1 P32246 1/20 0.31
CCR8 P51685 1/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146256 0.78 ALDH1A1 (0.39) CYP2A6CYP1A2MAPTALDH1A1MEN1
SCHEMBL11265175 0.78 CYP1A2 (0.38) CYP2A6CYP1A2MAPTALDH1A1MEN1
SCHEMBL7003885 0.78 CYP2A6 (0.37) CYP2A6CYP1A2MAPTALDH1A1MEN1
SCHEMBL5539181 0.77 TP53 (0.39) CYP2A6ALDH1A1LMNATSHRHTT
SCHEMBL10740801 0.76 TP53 (0.37) ALDH1A1LMNATSHRHTTHSD17B10
SCHEMBL21496349 0.75 HPGD (0.39) CYP2A6CYP1A2MAPTALDH1A1MEN1
SCHEMBL6415623 0.74 LMNA (0.36) LMNA
SCHEMBL22749378 0.73 CYP1A2 (0.35) CYP2A6CYP1A2ALDH1A1MEN1KMT2A
SCHEMBL5145125 0.73 CYP1A2 (0.46) CYP2A6CYP1A2ALDH1A1MEN1KMT2A
SCHEMBL1450256 0.72 HSD17B10 (0.41) CYP1A2MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
US-20230375537-A1 BASE MATERIAL FOR MANUFACTURING SENSOR FOR ANALYZING DETECTION OBJECT, SENSOR FOR ANALYZING DETECTION OBJECT, AND METHOD FOR ANALYZING DETECTION OBJECT NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2023-11-23 US disclosed
EP-4220160-A1 BASE MATERIAL FOR MANUFACTURING SENSOR FOR ANALYZING DETECTION OBJECT, SENSOR FOR ANALYZING DETECTION OBJECT, AND METHOD FOR ANALYZING DETECTION OBJECT National University Corporation Kobe University (JP) 2023-08-02 EP disclosed
CN-116324409-A Substrate for producing sensor for analysis of detection object, and analysis method of detection object 国立大学法人神户大学 2023-06-23 CN disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-20230152306-A1 NANOPARTICLES FOR SENSING USE AND PRODUCTION METHOD FOR SAME TearExo Inc. (JP) 2023-05-18 US disclosed
CN-115667932-A Nanoparticle for sensing and method for producing same 提尔埃克斯奥股份有限公司 2023-01-31 CN disclosed
EP-4113118-A1 NANOPARTICLES FOR SENSING USE AND PRODUCTION METHOD FOR SAME TearExo Inc. (JP) 2023-01-04 EP disclosed
CN-110473989-B Method for manufacturing organic light emitting element 株式会社LG化学 2022-05-27 CN disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 US disclosed
US-4118383-A COLORFAST ON POLYESTER AND METALLIZED POLYPROPYLENE FIBERS AMERICAN COLOR & CHEMICAL CORPORATION (US) 1978-10-03 US disclosed
US-4096115-A Ultraviolet light stabilized polymers EASTMAN KODAK COMPANY (US) 1978-06-20 US disclosed
US-4082517-A CYCLOPENTADIENYL MANGANESE ANTIKNOCK ETHYL CORPORATION (US) 1978-04-04 US disclosed
US-RE29488-E CYCLOPENTADIENYL MANGANESE TRICARBONYL, CARBOXYMETHOXY-SUCCINIC ACIDS ETHYL CORPORATION (US) 1977-12-06 US disclosed
US-4052171-A FUEL COMPOSITIONS AND ADDITIVE MIXTURES CONTAINING METHANETRICARBOXYLATES FOR REDUCING EXHAUST GAS CATALYST PLUGGING ETHYL CORPORATION (US) 1977-10-04 US disclosed
US-4005992-A CYCLOPENTADIENYL MAGNESIUM TRICARBONYL, OXYMETHYLENEMALONIC ACIDS OR ESTERS ETHYL CORPORATION (US) 1977-02-01 US disclosed
US-4005993-A CYCLOPENTADIENYL MANGANESE TRICARBONYL, OXYALKYL-MALONIC ACIDS OR ESTERS ETHYL CORPORATION (US) 1977-02-01 US disclosed
US-3962246-A BROMO-PROPANOL DERIVATIVES AS FLAME RETARDANTS SANDOZ LTD. (CH) 1976-06-08 US disclosed
US-3958955-A CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK ETHYL CORPORATION (US) 1976-05-25 US disclosed
US-3950145-A ANTIKNOCK ETHYL CORPORATION (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 CYP2A6 2893/4885CYP1A2 1066/4885MAPT 3852/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 CYP2A6 2893/4885CYP1A2 1066/4885MAPT 3852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.