Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30710477 | 0.89 | MEN1 (0.41) | MEN1KMT2ANR1H2ESR2ABHD6 | |
| SCHEMBL30710394 | 0.85 | CHRM3 (0.41) | MEN1KMT2ACHRM3USP30NR1H2 | |
| SCHEMBL20912490 | 0.81 | LHCGR (0.43) | MEN1KMT2ACHRM3USP30NR1H2 | |
| SCHEMBL24528815 | 0.80 | NR1H2 (0.45) | MEN1KMT2AUSP30NR1H2ESR2 | |
| SCHEMBL30878523 | 0.80 | NR1H2 (0.45) | MEN1KMT2AUSP30NR1H2ESR2 | |
| SCHEMBL17410272 | 0.78 | MEN1 (0.38) | MEN1KMT2AUSP30NR1H2ESR2 | |
| SCHEMBL20912499 | 0.78 | LHCGR (0.43) | CHRM3NR1H2GHSR | |
| SCHEMBL20912497 | 0.78 | LHCGR (0.57) | — | |
| SCHEMBL27276905 | 0.78 | ESR1 (0.51) | CHRM3NR1H2ESR2GHSRRORC | |
| SCHEMBL17410304 | 0.77 | MEN1 (0.39) | MEN1KMT2AUSP30NR1H2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250439-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |