Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LHCGR | P22888 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30710404 | 0.90 | LMNA (0.42) | HDAC1HDAC6NR1H2GHSRUCHL1 | |
| SCHEMBL30710250 | 0.90 | LMNA (0.42) | HDAC1HDAC6NR1H2GHSRUCHL1 | |
| SCHEMBL29560706 | 0.85 | TRPV1 (0.52) | CHRM3TRPM8MEN1KMT2A | |
| SCHEMBL30710358 | 0.85 | MEN1 (0.48) | CHRM3TRPM8NR1H2GHSRUSP30 | |
| SCHEMBL30710500 | 0.82 | TRPM8 (0.41) | TRPM8NR1H2UCHL1USP30MEN1 | |
| SCHEMBL29405461 | 0.81 | NR1H2 (0.43) | HDAC1HDAC6NR1H2GHSRUCHL1 | |
| SCHEMBL30734308 | 0.79 | ESR1 (0.51) | CHRM3GHSRMEN1KMT2AALDH1A1 | |
| SCHEMBL27276906 | 0.79 | ESR1 (0.51) | CHRM3GHSRMEN1KMT2AALDH1A1 | |
| SCHEMBL30734235 | 0.79 | ESR1 (0.51) | CHRM3GHSRMEN1KMT2AALDH1A1 | |
| SCHEMBL30710294 | 0.76 | NR1H2 (0.42) | HDAC1HDAC6NR1H2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250439-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |