Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071054 | 1.00 | UBE2M (0.53) | UBE2MDCUN1D1CCR2SIGMAR1HDAC3 | |
| SCHEMBL3072521 | 1.00 | UBE2M (0.53) | UBE2MDCUN1D1CCR2SIGMAR1HDAC3 | |
| SCHEMBL3072524 | 1.00 | UBE2M (0.53) | UBE2MDCUN1D1CCR2SIGMAR1HDAC3 | |
| SCHEMBL3121018 | 0.84 | UBE2M (0.60) | UBE2MDCUN1D1SIGMAR1POLBDRD2 | |
| SCHEMBL2221237 | 0.84 | UBE2M (0.60) | UBE2MDCUN1D1SIGMAR1POLBDRD2 | |
| SCHEMBL2221234 | 0.84 | UBE2M (0.60) | UBE2MDCUN1D1SIGMAR1POLBDRD2 | |
| SCHEMBL3121007 | 0.84 | UBE2M (0.60) | UBE2MDCUN1D1SIGMAR1POLBDRD2 | |
| SCHEMBL3118452 | 0.84 | UBE2M (0.60) | UBE2MDCUN1D1SIGMAR1POLBDRD2 | |
| SCHEMBL9721654 | 0.81 | DRD4 (0.61) | UBE2MDCUN1D1SIGMAR1DRD2DRD4 | |
| SCHEMBL9721659 | 0.81 | DRD4 (0.61) | UBE2MDCUN1D1SIGMAR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | BASKARAN SUBRAMANIAN | 2010-10-28 | — | — | US | disclosed |
| WO-2010091411-A1 | PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272680-A1 | Piperidinyl Cyclic Amido Antiviral Agents | ZC3HAV1, MAVS, EIF2AK2 | UBE2M 3795/4885DCUN1D1 1892/4885CCR2 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.