Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410221 | 1.00 | L3MBTL1 (0.50) | L3MBTL1PLK1ALDH1A1MAPTRECQL | |
| SCHEMBL19410199 | 0.84 | PLK1 (0.46) | L3MBTL1PLK1ALDH1A1MAPTRECQL | |
| SCHEMBL19410146 | 0.82 | SLC7A5 (0.38) | L3MBTL1ALDH1A1MAPTRECQLMTNR1A | |
| SCHEMBL30343690 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTRECQLHDAC10 | |
| SCHEMBL7434865 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTRECQLHDAC10 | |
| SCHEMBL16099677 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTRECQLHDAC10 | |
| SCHEMBL30002479 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTRECQLHDAC10 | |
| SCHEMBL16099676 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTRECQLHDAC10 | |
| SCHEMBL19410197 | 0.77 | SLC16A3 (0.46) | L3MBTL1ALDH1A1MAPTRECQLSLC7A5 | |
| SCHEMBL5956307 | 0.77 | GAA (0.54) | L3MBTL1ALDH1A1MAPTHDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997698-B | Immunomodulatory agents acting as PD-1 antagonists | 百时美施贵宝公司 | 2023-12-26 | — | — | CN | disclosed |